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- W2364941992 abstract "Objective:To explore the influence of Tongmaiyizhi decoction on blood-lipid changes in ischemia reperfusion model rats with hyperlipemia.Methods:Animal models with vascular dementia were prepared by cerebral ischemia-reperfusion in hyperlipidemia model rats.We observed the levels of total cholesterol,triglycerides,blood viscosity and platelet aggregation rate between model group and administration group.Results:The levels of serum TG in four groups,i.e.,blank control group,sham-operated group,model group and Tongmaiyizhi group,were(0.379±0.104),(0.385±0.161),(0.485±0.223),(0.285±0.154) mmol·L-1,respectively.The levels of serum T-CHO were(1.319±0.242),(4.338±1.574),(4.942±1.468),(3.351±1.098) mmol·L-1.Blood viscosity were(23.43±5.08),(17.05±1.34),(17.56±2.44),(16.51±1.811) s-1.Platelet aggregation rate in 1 min were(29.73±15.10)%,(40.62±13.46)%,(52.40±21.02)%,(30.00±12.23)%,and in 5 minute were(40.18±20.72)%,(37.02±25.47)%,(58.26±23.19)%,(29.25±23.98)%.The levels of serum TG,T-CHO,blood viscosity and platelet aggregation rate in administration group were obviously lower than those in the model group(all P0.05).Conclusions:Tongmaiyizhi decoction can adjust and improve blood lipid,hemorrheology,and the status of hyper-viscosity and hyper-aggregation caused by hypirlipidemia that is in the range of turbid phlegm and blood stasis syndrome." @default.
- W2364941992 created "2016-06-24" @default.
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- W2364941992 date "2010-01-01" @default.
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- W2364941992 title "Effect of Tongmaiyizhi decoction on blood-lipid changes in model rats with phlegm stagnation and blood stasis" @default.
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