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- W2364942057 abstract "Objective: To study the clinical value of TSH-receptor antibody(TRAb) in the diagnosis of autoimmune thyroid disease and compare the results achieved by radioreceptor assay(RRA )with enzyme immunoassay. Methods: Serum TRAb levels were determined with RRA and enzyme immunoassay in patients with Graves’ disease(GD), chronic lymphocytic thyroiditis(hypothyrosis)and the healthy persons. Results: The positive rates of GD patients group and hypothyrosis patients group by RRA were 85.7%and 64.3% respectively, which were significant higher than control group (P0.01). The positive rates of GD patients group and hypothyrosis patients group by enzyme immunoassay were 25.0%and 21.4% respectively.This assay has no significant difference than control group (P0.05). Conclusion: Determination of serum TRAb levels helps to the diagnosis of GD. Compare with enzyme immunoassay, the sensitivity and specificity of RRA are better, and RRA is suitable to clinical application." @default.
- W2364942057 created "2016-06-24" @default.
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- W2364942057 date "2008-01-01" @default.
- W2364942057 modified "2023-09-25" @default.
- W2364942057 title "Comparison of clinical application of two detection methods of TSH-receptor antibody" @default.
- W2364942057 hasPublicationYear "2008" @default.
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