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- W2364955092 abstract "Objective To study the expression of CD105,VEGF and TGF-β1 in colorectal cancer and their relationship with angiogenesis.Methods Immunohistochemical staining(S-P method) for VEGF,TGF-β1 and microvessel density(MVD) with marked CD105 were performed in 60 cases of colorectal cancer.Results The value of MVD with marked CD105 was 36.50±9.43 in colorectal cancer.The positive rates of VEGF and TGF-β1 were 68.3% and 75.0%,respectively.The value of MVD and the expression of VEGF and TGF-β1 were significantly correlated to the tumor depth of invasion,lymphonode metastasis and Dukes stages(P0.05).The expression of VEGF and TGF-β1 was positively correlated to MVD(P0.01).There was a significant positive correlation between the expressions of TGF-β1 and VEGF(P0.05).Conclusion CD105,VEGF and TGF-β1 are closely correlated,which may be valuable markers in evaluating the angiogenesis,invasion and metastasis in colorectal cancer when combined." @default.
- W2364955092 created "2016-06-24" @default.
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- W2364955092 date "2006-01-01" @default.
- W2364955092 modified "2023-09-23" @default.
- W2364955092 title "Expression of CD105,VEGF and TGF-β1 in colorectal cancer and their relationship to invasion,metastasis and angiogenesis" @default.
- W2364955092 hasPublicationYear "2006" @default.
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