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- W2364960712 abstract "The inclusion complex of fluorouracil-b-cyclodextrin sulfate was prepared using solvent evaporationmethod. Dimethylnitrosoamine was used to induce liver cancer in rats. A HPLC method was used for determination offluorouracil in the liver homogenate. The bulk drug (as control group)and the inclusion complex solution were directlyinjected into rats liver by portal vein, respectively. The results showed that in the control group the concentration offluorouracil in normal issue and tumour issue didnt have significant difference(P0.05), while in the inclusion complexgroup the difference was signifcant(P0.01). The drug concentration in liver homogenate was determined afteradministration of both solutions through rat caudal vein, respectively. The results showed that the drug concentration intwo groups was significantly different at each sampling time(P0.01)." @default.
- W2364960712 created "2016-06-24" @default.
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- W2364960712 date "2004-01-01" @default.
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- W2364960712 title "Targeting Effect of Inclusion Complex of Fluorouracil-β-cyclodextrin Sulfate" @default.
- W2364960712 hasPublicationYear "2004" @default.
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