Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364982124> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2364982124 endingPage "500" @default.
- W2364982124 startingPage "488" @default.
- W2364982124 abstract "In the hypothermic dog heart-lung preparation, norepinephnine causes a triphasic contractile force pattern characterized by an initial, brief increase in contractile force, a transient decrease in contractile force and a final prolonged increase in contractile force. These triphasic changes are reflected in the cardiac output, systolic blood pressure and left atnial pressure, and are similar to those observed in vivo . During hypothermia, ouabain increases contractile force and cardiac output and decreases left atrial pressure. Ouabain also blocks the two stimulant responses to norepinephnine and enhances the depressant response to norepinephrine. These effects of norepinephnine before and after ouabain are not caused by changes in cardiac rhythm, coronary flow, extraction of oxygen, cardiac content of adenosine triphosphate and creatine phosphate or peripheral vascular reactivity. Infusion of norepinephnine in vivo at 38°C only increases force, but at 28-30° causes a triphasic response characterized by a brief increase in force, persistence of the phase of cardiac depression throughout the infusion and development of the third (stimulant) phase only after the infusion is stopped. Infusion of norepinephrine after ouabain causes only cardiac depression. These data suggest that two distinct processes are involved in the responses to norepinephrine during hypothermia, one producing a positive inotropic response and the other a negative inotropic response." @default.
- W2364982124 created "2016-06-24" @default.
- W2364982124 creator A5021232169 @default.
- W2364982124 creator A5030605351 @default.
- W2364982124 date "1966-06-01" @default.
- W2364982124 modified "2023-09-23" @default.
- W2364982124 title "Cardiovascular function, oxygen extraction and labile nucleotide content of cardiac muscle during norepinephrine-induced depression of digitalized, hypothermic dog heart muscle." @default.
- W2364982124 cites W1944167357 @default.
- W2364982124 cites W2259424745 @default.
- W2364982124 cites W2411558849 @default.
- W2364982124 cites W35333695 @default.
- W2364982124 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5922314" @default.
- W2364982124 hasPublicationYear "1966" @default.
- W2364982124 type Work @default.
- W2364982124 sameAs 2364982124 @default.
- W2364982124 citedByCount "0" @default.
- W2364982124 crossrefType "journal-article" @default.
- W2364982124 hasAuthorship W2364982124A5021232169 @default.
- W2364982124 hasAuthorship W2364982124A5030605351 @default.
- W2364982124 hasConcept C111566952 @default.
- W2364982124 hasConcept C126322002 @default.
- W2364982124 hasConcept C134018914 @default.
- W2364982124 hasConcept C139940330 @default.
- W2364982124 hasConcept C155710745 @default.
- W2364982124 hasConcept C164705383 @default.
- W2364982124 hasConcept C178790620 @default.
- W2364982124 hasConcept C185592680 @default.
- W2364982124 hasConcept C2777390192 @default.
- W2364982124 hasConcept C2778198053 @default.
- W2364982124 hasConcept C2778514916 @default.
- W2364982124 hasConcept C2778996579 @default.
- W2364982124 hasConcept C2779133857 @default.
- W2364982124 hasConcept C513476851 @default.
- W2364982124 hasConcept C537181965 @default.
- W2364982124 hasConcept C71924100 @default.
- W2364982124 hasConcept C84393581 @default.
- W2364982124 hasConceptScore W2364982124C111566952 @default.
- W2364982124 hasConceptScore W2364982124C126322002 @default.
- W2364982124 hasConceptScore W2364982124C134018914 @default.
- W2364982124 hasConceptScore W2364982124C139940330 @default.
- W2364982124 hasConceptScore W2364982124C155710745 @default.
- W2364982124 hasConceptScore W2364982124C164705383 @default.
- W2364982124 hasConceptScore W2364982124C178790620 @default.
- W2364982124 hasConceptScore W2364982124C185592680 @default.
- W2364982124 hasConceptScore W2364982124C2777390192 @default.
- W2364982124 hasConceptScore W2364982124C2778198053 @default.
- W2364982124 hasConceptScore W2364982124C2778514916 @default.
- W2364982124 hasConceptScore W2364982124C2778996579 @default.
- W2364982124 hasConceptScore W2364982124C2779133857 @default.
- W2364982124 hasConceptScore W2364982124C513476851 @default.
- W2364982124 hasConceptScore W2364982124C537181965 @default.
- W2364982124 hasConceptScore W2364982124C71924100 @default.
- W2364982124 hasConceptScore W2364982124C84393581 @default.
- W2364982124 hasIssue "3" @default.
- W2364982124 hasLocation W23649821241 @default.
- W2364982124 hasOpenAccess W2364982124 @default.
- W2364982124 hasPrimaryLocation W23649821241 @default.
- W2364982124 hasRelatedWork W1623857162 @default.
- W2364982124 hasRelatedWork W1902904704 @default.
- W2364982124 hasRelatedWork W1976232206 @default.
- W2364982124 hasRelatedWork W1990181720 @default.
- W2364982124 hasRelatedWork W1994320988 @default.
- W2364982124 hasRelatedWork W2030499433 @default.
- W2364982124 hasRelatedWork W2121908972 @default.
- W2364982124 hasRelatedWork W2152949957 @default.
- W2364982124 hasRelatedWork W2278259625 @default.
- W2364982124 hasRelatedWork W2364982124 @default.
- W2364982124 hasVolume "152" @default.
- W2364982124 isParatext "false" @default.
- W2364982124 isRetracted "false" @default.
- W2364982124 magId "2364982124" @default.
- W2364982124 workType "article" @default.