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- W2364982390 abstract "Aim: To investigate the expression of cyclooxygenase-2 (COX-2)and motor function of Barrett's esophagus(BE).Methods: The clinical characteristics of sixty-two BE patients were analyzed, Motor function of esophagus was detected in 21 cases,and the expression of COX-2 in mucosa were detected in 37 cases. Twenty healthy individuals and 23 patients with reflux esophagitis (RE) were the control.Results: Lower esophageal sphincter (LES)pressure and distal esophageal contraction amplitude of BE patients were lower than those of RE and controls (P0.05). The expression of COX-2 were found in 20 out of 24 BE without dysplasia, and 12 out of 13 BE with dysplasia, but not in normal mucosa. Conclusion: The dysfunction of the LES is the main mechanism of BE, and COX-2 expression is an early event in the development of BE." @default.
- W2364982390 created "2016-06-24" @default.
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- W2364982390 date "2006-01-01" @default.
- W2364982390 modified "2023-09-23" @default.
- W2364982390 title "Expression of COX-2 in Barrett's esophageal tissue and esophagus motor function" @default.
- W2364982390 hasPublicationYear "2006" @default.
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