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- W2364987400 abstract "Objective To screen the anti- radiation activity of total polyphenols from Elaeagnus angustifolia seeds. Methods The radiation injury model of Human skin fibroblasts( HSF) were established by irradiating HSF with different dosages of X- ray,then MTT assay was used to detect the cell's proliferation activity after being treated by different concentrations of total polyphenols. Results The proliferation inhibition effect of X- ray on HSF was positively correlated with the irradiated dose. This kind of effect in16 Gy group was more significant compared with 2 Gy,4 Gy and 8 Gy groups( P 0. 01) respectively. Compared with model group,after the cell was irradiated by 16 Gy X- ray,every total polyphenols group was statistically significant at all- time points( P 0. 01) except 100 μg/ml-48 h. After irradiation for 2h,radiation protection effect became dose dependent,but the radiation protection effect of the dosage groups decreased with the elongation of time. Conclusion X- ray irradiation can induce obvious damage to HSF. Total polyphenols can protect HSF from radiation." @default.
- W2364987400 created "2016-06-24" @default.
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- W2364987400 date "2013-01-01" @default.
- W2364987400 modified "2023-10-13" @default.
- W2364987400 title "Anti- radiation activity screening of total polyphenols from Elaeagnus angustifolia Seeds" @default.
- W2364987400 hasPublicationYear "2013" @default.
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