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- W2364987593 abstract "Objective To construct a mouse model for Neisseria gonorrhoeae genital infection. Methods Female BALB/c mice were treated with 17-β-estradiol and inoculated intravaginally with wild type gonococcus FA1090. The genital swab were verified by the WGC agar plate. The vaginal excretes smears were stained with wright stain and viewed under light microscopy to determine the percentage of PMNs among 100 vaginal cells. Results Survival of gonococci in the animal genital tract continued for an average of 8 days. The stained vaginal smears showed that the pathogens adhered to the epithelial cells and neutrophils.Inflammation occurred in over 88% of infected mice. Conclusion A mouse model for Neisseria gonorrhoeae infection was constructured successfully, which may be used for the study of pathogenicity, virulence and treatment of Neisseria gonorrhoeae infection." @default.
- W2364987593 created "2016-06-24" @default.
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- W2364987593 date "2005-01-01" @default.
- W2364987593 modified "2023-09-23" @default.
- W2364987593 title "Establishment of A Mouse Model for Neisseria gonorrhoeae Infection" @default.
- W2364987593 hasPublicationYear "2005" @default.
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