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- W2365017377 abstract "Objective To explore the effect of different proportions of mixed blood exchange transfusion on blood circulation in neonates with hemolytic disease.Methods Thirty-one newborn infants with hemolytic disease were treated by peripheral arteriovenous synchronization of exchange transfusion with different proportions mixed blood.AB type plasma was mixed with O type red blood cell(RBC) washing.The proportion for the treatment group was 1:1(the O type RBCs 2 U:the AB type plasma 200 mL),by exchange transfusion of haplotypes,in accordance with 80±mL/kg;the proportion for control group was 2:1(the O type RBC 4 U:the AB type plasma 200 mL),by exchange transfusion of double in accordance with 150-180 mL/kg.The indicators were detected,such as the exchange rate of neonatal serum bilirubin,RBC,hemoglobin(Hb),hematocrit(HCT),and the exchange transfusion quantity and days of hospitalization before and after the exchange transfusion were analyzed.Results The exchange rate of serum bilirubin of treatment group and control group was (44.92±3.99)% and (45.69±5.06)%,respectively,there was no significant difference between 2 groups(P=0.639),there was no significant difference of hospitalization days[(8.13±1.13) d vs(8.19±0.91) d]between 2 groups(P=0.884).After exchange transfusion in treatment group,the average level of the RBC,Hb and HCT were increased(P0.05,0.01,0.001),although the level of increase was slightly lower than those of control group,but had been basically correct anemia,clinical symptoms improve.The amount of exchange transfusion quantit in treatment group was lower than that of control group(P=0).Conclusions The exchange transfusion with 1:1 haplotypes mixed blood on neonatal hemolytic disease can decrease the level of bilirubin in blood and reduce the amount of exchange transfusion as well." @default.
- W2365017377 created "2016-06-24" @default.
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- W2365017377 date "2008-01-01" @default.
- W2365017377 modified "2023-09-27" @default.
- W2365017377 title "Effect of Different Proportions of Mixed Blood Exchange Transfusion on Blood Internal Environment in Neonates with Hemolytic Disease" @default.
- W2365017377 hasPublicationYear "2008" @default.
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