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- W2365049291 abstract "Objective To investigate the hemodynamic changes induced by CO 2 pneumoperitoneum and possible mechanism in rabbits with emphysema.Methods There set normal control group,experimental group (only inserted with Veress needle) and pneumoperitoneum group,of which the third group was further divided into five time points,ie,0,2,4,6 and 18 hours after pneumoperitoneum stopped.After rabbit models with emphysema were established,the abdominal cavity of these models were gradually insufflated with CO 2 and maintained at the pressure of 10mm Hg and 15mm Hg (1mm Hg=0.133 kPa) respectively for two hours by using close method.We tested blood gas (pH,PaCO 2 and PaO 2) in every time points before and after laparoscopy.Results pH and PaO 2 reduced but PaCO 2 in the arterial blood increased 0 and 2 hours after laparoscopy.Further,pH and PaO 2 increased but PaCO 2 reduced 3,6 and 18 hours after laparoscopy.The changes were more evident in the groups at 15 mm Hg pressure than those at 10 mm Hg pressure.Conclusion Under CO 2 pneumoperitoneum,the animals with emphysema are apt to hemodynamic disorder,pulmonary ventilation dysfunction,decreased compliance and pulmonary function damage.In the meantime,the pulmonary function damage worsens with the pressure of CO 2 pneumoperitoneum." @default.
- W2365049291 created "2016-06-24" @default.
- W2365049291 creator A5059677383 @default.
- W2365049291 date "2004-01-01" @default.
- W2365049291 modified "2023-09-23" @default.
- W2365049291 title "Hemodynamic changes induced by CO_2 pneumoperitoneum in rabbits with emphysema" @default.
- W2365049291 hasPublicationYear "2004" @default.
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