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- W2365089366 abstract "Objective To observe the changes of the intercellular spaces of squamous epithelium of lower esophagus in gastroesophageal reflux disease(GERD) with esomeprazole.Methods Measure the DIS of 5 healthy volunteers by random selection to be the normal reference value.Select 6 cases with non-erosive GERD(NERD) and 5 cases with reflux esophagitis(RE) to be objective observation in the treatment group.Biopsies were taken at 3～5 cm above the dentate line after 3 months treatment with esomeprazole to observe and analyze the DIS changes than no-treatment.Results After 3 months threatment,5/6 cases'DIS had been normal in NERD group(83.3%),4/5 cases'DIS had been normal in RE group(80%).The 2 cases'DIS hadn't been normal and their clinical symptoms hadn't been disappear.Conclusion After 3 months threatment with esomeprazole in GERD,the changes of DIS is remarkable,the improvement of the clinical symptoms is remarkable too." @default.
- W2365089366 created "2016-06-24" @default.
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- W2365089366 date "2012-01-01" @default.
- W2365089366 modified "2023-09-23" @default.
- W2365089366 title "Changes of the intercellular spaces of squamous epithelium of lower esophagus in gastroesophageal reflux disease with esomeprazole" @default.
- W2365089366 hasPublicationYear "2012" @default.
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