Matches in SemOpenAlex for { <https://semopenalex.org/work/W2365111876> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2365111876 abstract "Objective To establish an HPLC method for quantitative determination of triamcinolone acetonide acetate and econazole nitrate in vitro percutaneous solution,and investigate the ability of percutaneous penetration of triamcinolone acetonide acetate and econazole nitrate cream.Methods Chromatographic column;C8(5μm)(SP-120-5-C8-AP);Mobile phase:gradient elution:0.094%anhydrsodium hexanesulfonate[purification water - cyanide - isopropyl alcohol(720:40:40)](adjust the pH to 3 with 85%phosphoric acid)as mobile phase A,0.094%sodium hexanesulfonate[purification water - methanol(100:900)](adjust the pH to 3 with 85%phosphoric acid) as mobile phase B.Detection wavelength:227 ran.Flow rate:1.0 mL/min.Injection;20μl.Improved Franz type diffusion cells were used in vitro permeation studies and excised minipigs skins in vitro were used as transdermal barrier.The concentration of triamcinolone acetonide acetate and econazole nitrate in the receptor solution was determined by HPLC to investigate its cumulative permeation quantities at different time respectively and compared with that of the commercial cream.Results The regression equation of triamcinolone econazole nitrate was linear in the range of 0.50μg/mL-4.00μg/mL(A = 0.8834×C+0.05075,r =0.9991).The average recovery was all between 85% - 115%.A good linear relationship existed between the cumulative penetration quantities and the time.There was no significant difference in the permeation quantities between the self - made and commercial cream.Conclusion The method is simple,rapid,and accurate,therefore is a better method to evaluate the characteristic of permeation for triamcinolone acetonide acetate and econazole nitrate cream." @default.
- W2365111876 created "2016-06-24" @default.
- W2365111876 creator A5041434082 @default.
- W2365111876 date "2011-01-01" @default.
- W2365111876 modified "2023-09-22" @default.
- W2365111876 title "Determination of Percutaneous Absorption of Econazole Nitrate after Experiment of Percutaneous Reabsorption of Triamcinolone Acetonide Acetate and Econazole Nitrate Cream" @default.
- W2365111876 hasPublicationYear "2011" @default.
- W2365111876 type Work @default.
- W2365111876 sameAs 2365111876 @default.
- W2365111876 citedByCount "0" @default.
- W2365111876 crossrefType "journal-article" @default.
- W2365111876 hasAuthorship W2365111876A5041434082 @default.
- W2365111876 hasConcept C141071460 @default.
- W2365111876 hasConcept C16005928 @default.
- W2365111876 hasConcept C179998833 @default.
- W2365111876 hasConcept C185592680 @default.
- W2365111876 hasConcept C2776778513 @default.
- W2365111876 hasConcept C2777229883 @default.
- W2365111876 hasConcept C2778903070 @default.
- W2365111876 hasConcept C2779548794 @default.
- W2365111876 hasConcept C2911222091 @default.
- W2365111876 hasConcept C41625074 @default.
- W2365111876 hasConcept C43617362 @default.
- W2365111876 hasConcept C50670333 @default.
- W2365111876 hasConcept C55493867 @default.
- W2365111876 hasConcept C71924100 @default.
- W2365111876 hasConceptScore W2365111876C141071460 @default.
- W2365111876 hasConceptScore W2365111876C16005928 @default.
- W2365111876 hasConceptScore W2365111876C179998833 @default.
- W2365111876 hasConceptScore W2365111876C185592680 @default.
- W2365111876 hasConceptScore W2365111876C2776778513 @default.
- W2365111876 hasConceptScore W2365111876C2777229883 @default.
- W2365111876 hasConceptScore W2365111876C2778903070 @default.
- W2365111876 hasConceptScore W2365111876C2779548794 @default.
- W2365111876 hasConceptScore W2365111876C2911222091 @default.
- W2365111876 hasConceptScore W2365111876C41625074 @default.
- W2365111876 hasConceptScore W2365111876C43617362 @default.
- W2365111876 hasConceptScore W2365111876C50670333 @default.
- W2365111876 hasConceptScore W2365111876C55493867 @default.
- W2365111876 hasConceptScore W2365111876C71924100 @default.
- W2365111876 hasLocation W23651118761 @default.
- W2365111876 hasOpenAccess W2365111876 @default.
- W2365111876 hasPrimaryLocation W23651118761 @default.
- W2365111876 hasRelatedWork W114194523 @default.
- W2365111876 hasRelatedWork W145309045 @default.
- W2365111876 hasRelatedWork W1988487146 @default.
- W2365111876 hasRelatedWork W2005949422 @default.
- W2365111876 hasRelatedWork W2085104905 @default.
- W2365111876 hasRelatedWork W2184124143 @default.
- W2365111876 hasRelatedWork W2365356388 @default.
- W2365111876 hasRelatedWork W2419101655 @default.
- W2365111876 hasRelatedWork W2767954663 @default.
- W2365111876 hasRelatedWork W2799401323 @default.
- W2365111876 hasRelatedWork W2921294565 @default.
- W2365111876 hasRelatedWork W3008556302 @default.
- W2365111876 hasRelatedWork W3030352115 @default.
- W2365111876 hasRelatedWork W3092280533 @default.
- W2365111876 hasRelatedWork W3108703682 @default.
- W2365111876 hasRelatedWork W3122297159 @default.
- W2365111876 hasRelatedWork W91719426 @default.
- W2365111876 hasRelatedWork W2182109744 @default.
- W2365111876 hasRelatedWork W3151111412 @default.
- W2365111876 hasRelatedWork W3200071482 @default.
- W2365111876 isParatext "false" @default.
- W2365111876 isRetracted "false" @default.
- W2365111876 magId "2365111876" @default.
- W2365111876 workType "article" @default.