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- W2365123786 abstract "Objective:To establish the methods for neonatal screening and further confirmation of Glucose-phosphatede hydrogenase deficiency.Methods:G6PD activity was measured by using fluorescence spot test(FST) with the dry blood specimens on the filter paper for neonatal screening.Babies whose specimens showed to be doubtful positive result will becalled back.G6PD/6PGD rate test of venous blood specimens was further performed for confirmation.At the same time,analyzing the result according to his or her parent blood.Results:G6PD deficiency rate was4.53%(4321 /95 471) in FST for screening 95 471 newbabies.The accurate diagnosis rate was 4.20%(4009 /95 471),The conformation rate of FST and G6PD/6PGD rate test for G6PD deficiency was 92.78% ;The severe deficiency groups was 100% ;The middle deficiency groups was 86.13% ;The consistency of the EQA result with the feedback result is 100%.Conclusion:FST is used in neonatal screening of G6PD deficiency because of its high sensitivity and specificity and accuracy.The method is simple and convenient and shortcut and low-costexes.It can test lots of blood specimens on the filter paper.At the same time,G6PD/6PGD rate test is used for accurate diagnosis,They is very Favorable to diagnose and treat G6PD deficiency early in high incidence districts." @default.
- W2365123786 created "2016-06-24" @default.
- W2365123786 creator A5047944128 @default.
- W2365123786 date "2010-01-01" @default.
- W2365123786 modified "2023-09-26" @default.
- W2365123786 title "Fluorescence spot test and G6PD/6PGD rate test detecting of G6PD" @default.
- W2365123786 hasPublicationYear "2010" @default.
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