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- W2365133098 abstract "Objective To investigate the effects of differentiation on HL-60 cell induced by Chinese Medicine Kanglaite.Methods HL-60 cells at logarithmic growth phase were treated with Kanglaite.The growth curve of HL-60 cells was observed by cell count.Cell differentiation was assessed by morphology,NBT reduction test and the phagocytosis of cells.Results The HL-60 cells treated by 1 mg/ml Kanglaite for 6 days,the cell count are (10.3±1.1)×10 5个/ml,compare with control group's (20.5± 3.5)×10 5个/ml,the inhibitive effects are achieved with statistical significance(P0.05).The HL-60 cells treated by 1 mg/ml Kanglaite for 96 h,the trypan blue phogocytized rate (32.0±8.3)% of Kanglaite-treated cells are statistical higher than that (4.0±2.7)% of control group(P0.05).The NBT reduction rate (50.3±5.3)% of Kanglaite-treated cells are statistical differences with that (15.0±3.7)% of control group(P0.05).Conclusion HL-60 cells exposed to Kanglaite resulted in dose-depentent inhibitory,Morphologic changes on Kanglaite-treated HL-60 cells differentiated toward maturated leucocyte cell line age which displayed the NBT reduction and phagocytosis higer than that of control group.Kanglaite can obviously improve the differentiation of HL-60 cells." @default.
- W2365133098 created "2016-06-24" @default.
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- W2365133098 date "2004-01-01" @default.
- W2365133098 modified "2023-09-26" @default.
- W2365133098 title "Iducement of Differentiation of HL-60 Cells by Chinese Medicine Kanglaite" @default.
- W2365133098 hasPublicationYear "2004" @default.
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