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- W2365133754 abstract "Objective To study the correlation between level of C reactive protein in elderly hypertensive patients with their carotid artery intima media thickness and the effect of simvastatin intervention.Methods Two hundred cases of elderly patients with hypertension were randomly divided into three groups:control group(placebo),simvastatin group(simvastatin for 20 mg,qn),of fenofibrate group(of fenofibrate 200 mg,bid),respectively,before taking medicine,three month and six month after taking drug.Plasma C reactive protein concentration,carotid intima-media thickness,plasma cholesterol and triglyceride concentrations were detected.Different degrees of C reactive protein concentration were explored.By comparing C reactive protein and carotid artery intima-media thickness before and after treatment,study of simvastatin on atherosclerosis in elderly hypertension patients and the intervention effect of it was condncted.Results In elderly hypertensive patients with the increase of carotid artery intima-media thickness,C reactive protein concentration rose.Simvastatin could reduce C reactive protein concentration and carotid artery intima-media thickness,which showed that simvastatin could effectively control the degree of atherosclerosis in elderly patients with hypertension,inhibited atherosclerosis inflammation.Conclusion For elderly hypertensive patients,C reactive protein concentration and carotid artery intima-media thickness has significant correlation,which can be used as evaluation index for atherosclerosis.Simvastatin can inhibit atherosclerosis inflammation,reduce atherosclerotic level in elderly hypertensive patients." @default.
- W2365133754 created "2016-06-24" @default.
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- W2365133754 date "2012-01-01" @default.
- W2365133754 modified "2023-09-25" @default.
- W2365133754 title "Correlation between C reactive protein and carotid artery intima-media thickness in elderly hypertensive patients and the intervention with simvastatin" @default.
- W2365133754 hasPublicationYear "2012" @default.
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