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- W2365147219 abstract "Objective:To investigate the therapeutic effect of Candesartan combined with amiodarone in cardioversion of atrial fibrillation(AF) and the prevention of relapsing AF.Methods: 87 cases of persistent AF were randomly assigned into Candesartan plus Amiodarone group(44 cases) and Amiodarone group(43 cases).The rates of cardioversion,mean time for cardioversion,recurrence rates of AF and mean time to recurrence of each group were measured and compared,and the follow-up was 8 months.Results: There was no statistically significant difference in the rates of cardioversion between both groups(72.7% vs 51.2%,P0.05),while the mean time for cardioversion was significantly decreased in the Candesartan plus Amiodarone group compared with the Amiodarone group(12.6±4.1)days vs(15.3±5.5)days,P0.05;the recurrence rate of AF was obviously decreased in the Candesartan plus Amiodarone group(34.4% vs 63.6%,P0.05) with the mean time for cardioversion prolonged(175.3±41.5)days vs(90.9±36.5)days,P0.05,compared with that in the Amiodarone group.Conclusion:Treatment with the angiotensin receptor blocker Candesartan may have the synergistic effect in cardioversion of AF and maintainance of the sinus rhythm." @default.
- W2365147219 created "2016-06-24" @default.
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- W2365147219 date "2008-01-01" @default.
- W2365147219 modified "2023-09-24" @default.
- W2365147219 title "The Effect of Candesartan Plus Amiodarone in Cardioversion and Protection Against Recurrence of Atrial Fibrillation" @default.
- W2365147219 hasPublicationYear "2008" @default.
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