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- W2365172506 abstract "[Objective] The purpose was to enhance the output of succinate.[Method] Based on confirming significant factors through single factor experiment,the fermentation medium of Actinobacillus succinogenes JNUBE0709 was optimized by response surface method and the quadratic regression analysis was conducted on the optimized results by using Design-Expert software.[Result] It was confirmed through single factor experiment that the carbon source maltose was 50 g/L,nitrogen source yeast extract was 25 g/L and acid-alkali neutralizer MgCO3 was 40 g/L.The optimum concn.of 3 significant factors of maltose,yeast extract and MgCO3 obtained through optimization by response surface method were 51.1,24.5 and 40.4 g/L resp.Under this condition,the output of succinate was up to 33.45 g/L,increasing by 14.28 g/L than that before optimization and basically according with the model prediction value of 33.68 g/L.The interaction between maltose and yeast extract was not significant(P0.05) and that between MgCO3 and maltose,yeast extract were significant(P0.05).[Conclusion] The output of succinate after the fermentation medium of A. succinogenes was optimized by response surface method was enhanced by 74.49% than that before optimization." @default.
- W2365172506 created "2016-06-24" @default.
- W2365172506 creator A5073831860 @default.
- W2365172506 date "2008-01-01" @default.
- W2365172506 modified "2023-09-27" @default.
- W2365172506 title "Optimization of Fermentation Medium Producing Succinate by Response Surface Method" @default.
- W2365172506 hasPublicationYear "2008" @default.
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