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- W2365198669 abstract "AIM: To determine the percutaneous release of 1% tamoxifen (Tam) in three different stromata in vitro, and evaluate the affection of the treansdermal permeation of Tam from the three stromata in vitro. METHODS: The Franz diffusion cell was applied, and the samples was measured by UV(235 nm). RESULTS: In the different stromata of vaseline, PEG and carbopol, the permeation coefficient of Tam were 0, ( 1.06 ± 0.21 ) and ( 1.28 ± 0.20) μg/(cm 2·h), respectively. The cumulative amounts of release were 0, (31.9±2.4) and (23.5±2.9) μg/cm 2 in 24 h, and 0, (55±3) and (52±4) μg/cm 2 in 46 h, respectively. CONCLUSION: Hydrophilic ointment stromata for Tam, such as PEG and carbopol were better than vaseline stromata in the percutanous release." @default.
- W2365198669 created "2016-06-24" @default.
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- W2365198669 date "1999-01-01" @default.
- W2365198669 modified "2023-09-23" @default.
- W2365198669 title "Comparison of percutaneous release of tamoxifen ointment in three stromata in vitro" @default.
- W2365198669 hasPublicationYear "1999" @default.
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