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- W2365213467 abstract "Objective To find the distribution of CD4~+ T lymphocytes and viral loading before antiviral therapy,and to analyze the prevalence of drug resistance strains.Methods The absolute counts of CD4~+ T lym- phocytes were checked by flow cytometry and viral loading was detected by nucleic acid sequence based amplifica- tion(NASBA);RT-PCR was used to amplify the whole PR and partial RT region of HIV-1 genome,and then the information of drug resistance was obtained by submitting the sequence to the web http://hivdb,stanford,edu. Results There were 66.66% among the infected whose absolute counts of CD4~+ T lymphocytes were more than 350 counts/mm~3,and the mean value of viral loading was 3.784±1.048.Two cases had resistance mutations in all tested samples.Conclusion Most of the infected belonged to asymptomatic phase,and the viral loading was relatively high.Although the drug resistance strains occurred only at two cases,resistance has not a broad preva- lence in this region.It is vital to enhance the education of antiviral therapy among the infected." @default.
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- W2365213467 date "2007-01-01" @default.
- W2365213467 modified "2023-09-23" @default.
- W2365213467 title "Immunology and virology survey among the patients infected by HIV-1 before antiviral therapy in Ningxia Hui Authority" @default.
- W2365213467 hasPublicationYear "2007" @default.
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