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- W2365228085 abstract "Objective To compare the coaglation and fibrinolysis condition in patients with essential hypertension(EH) and in normal adult,to study influence of Losartan treatment on coagulation and fibrinolysis in patients with essential hypertension.Methods Plasminogen activator inhibitor-1(PAI-1)、von willebrand factor(vWF) and D-dimer(D-D) were assessed in 30 EH cases and 30 normal persons.In the meantime,30 normal persons were taken as control group.30 EH cases were treated with Losartan,50~100mg/d.After treatment for 4 weeks the above data were detected again.Results The PAI-1,D-D,vWF in EH cases were obviously higher than those in control group(P0.01).The PAI-1,D-D,vWF were decreased(P0.01) after treatment of Losartan.Conclusions The coagulation and fib rinolysis condition were changed in EH patients.The PAI-1、D-D、vWF were significantly higher in EH patients than those in control group.Losartan not only decreased obviously systolic blood pressure and diastolic blood pressure but also improved the coagulation and fibrinolysis condition in EH patients." @default.
- W2365228085 created "2016-06-24" @default.
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- W2365228085 date "2006-01-01" @default.
- W2365228085 modified "2023-09-23" @default.
- W2365228085 title "The influence of Losartan on PAI-1、D-D、vWF in patients with essential hypertension" @default.
- W2365228085 hasPublicationYear "2006" @default.
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