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- W2365242206 abstract "Objective To investigate the clinical effect of methylprednisolone and dexamethasone in treatment of allergic purpura. Methods Eighty-two patients with allergic purpura were selected in hospital from October 2010 to October 2012, who were randomly divided into two groups. 41 patients used dexamethasone as control group. 41 patients used methylprednisolone as observation group. Clinical symptoms improvement, clinical effect, adverse reaction were compared between two groups. Results Rash extinction time was (5.8±1.4) d, gastrointestinal tract reaction time was (2.7± 0.6) d, urine routine recovery time was (2.5 ±0.7) d, joint pain disappear time was (1.9 ±0.3) d in observation group, which were significantly lower than control group of (6.9 ±2.0), (4.1±0.9), (3.8±1.0), (3.1±0.5) d. Total effective rate in observation group (95.1%) was significantly higher than that of control group (80.5%), difference was statistically significant (P 0.05). Rate of adverse reactions (9.8%) in observation group was lower than control group (17.1%), difference was not statistically significant (P 0.05). Conclusion Clinical effect of methylprednisolone in treatment of allergic purpura is obvious better than dexamethasone, which can obviously shorten the duration of therapy and improve clinical symptoms. That has fewer adverse reactions and worth for clinical use." @default.
- W2365242206 created "2016-06-24" @default.
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- W2365242206 date "2013-01-01" @default.
- W2365242206 modified "2023-09-25" @default.
- W2365242206 title "Clinical comparative analysis of methylprednisolone and dexamethasone in treatment of allergic purpura" @default.
- W2365242206 hasPublicationYear "2013" @default.
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