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- W2365258761 abstract "Objective To investigate the protective effect of pretreatment with scarring moxibustion with incense stick in rats with cerebral ischemia-reperfusion injury.Methods SD rats(n=40) were randomly divided into control group,model group,pretreatment group with scarring moxibustion with moxa cone(moxa cone group) and pretreatment group with scarring moxibustion with incense stick(incense stick group).The rat model of middle cerebral artery occlusion(MCAO) and reperfusion was established by using thread approach.The moxa cone group and incense stick group were given the pretreatment of scarring moxibustion with moxa cone or incense stick on Zusanli(ST36) 3 days before ischemia-reperfusion.The rats were sacrificed after ischemia for 3 hours and reperfusion for 24 hours.The control group and model group were not given the pretreatment.The content changes of superoxide dismutase(SOD),malondialdehyde(MDA),nitric oxide(NO) and lactic acid(LD) were observed in all groups.Results The content of NO,LD and MDA decreased significantly,and content of SOD increased significantly in incense stick group compared with model group(P0.05,P0.01).The content of LD decreased significantly and content of SOD increased significantly in moxa cone group compared with model group(P0.05,P0.01).The content of LD decreased significantly in incense stick group compared with moxa cone group(P0.05).The content of NO,MDA and SOD had no differences between incense stick group and moxa cone group(P0.05).Conclusion The pretreatment of scarring moxibustion with incense stick and that with moxa cone can promote antioxidation in cells,reduce neurotoxicity mediated by NO and improve the energy metabolism in brain cells,and have significant protective effect in rats with cerebral ischemia-reperfusion.The effect of pretreatment of scarring moxibustion with incense stick is better than that of pretreatment of scarring moxibustion with moxa cone." @default.
- W2365258761 created "2016-06-24" @default.
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- W2365258761 date "2012-01-01" @default.
- W2365258761 modified "2023-09-25" @default.
- W2365258761 title "Protective effect of pretreatment with scarring moxibustion in rats with cerebral ischemia-reperfusion injury" @default.
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