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- W2365274080 abstract "Objective To investigate the coagulation disorder in the patients with SIRS and the relation to severity of SIRS/MODS,combining with the clinical screening of DIC,and provide evidences for the prevention and treatment of DIC.Methods The activity of AT Ⅲ was measured by chromogenic substrate method.The quantity of D dimer was measured by enzyme linked immunosorbent assay.Results The acitivity of AT Ⅲ was lower and the quantity of D dimer was significantly higher in SIRS group than that.Activity of AT Ⅲ in SIRS group with MODS was lower than SIRS group without MODS.The quantity of D dimer of SIRS group with MODS was significantly higher than that of SIRS group without MODS.The incidence of MODS in non DIC Patients was 32 0%,and it was 83 3% in patients with DIC(P0 01).Conclusion Patients with SIRS have abnormality in coagulation and fibrinolysis.It is suggested that DIC is the most important factor in disorder of coagulation and fibrinolytic system.It plays an important role in development form SIRS to MODS in severe patients." @default.
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- W2365274080 date "2001-01-01" @default.
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- W2365274080 title "The measurement of AT-III activity and D-dimer quantity in plasma from patients with SIRS" @default.
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