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- W2365281014 abstract "Objective:To investigate the effect of ambroxol on the immunological and respiratory function of patients with chronic obstructive pulmonary diseases(COPD)during the acute exacerbation episode.Methods:Xisty patients with COPD in the acute aggravation episode were randomly divided into groups and 30 health elderly subjects were recruited as controls for observing the percentage of neutrophilic granulocyte in the peripheral bolld and immunoglobulin IgA,IgG,IgM,complement of C3,and C4 in blood serum,with arterial blood gas analysis.Results:The neutrophilie granuloeytes were obviously increased in patients with COPD during the acute aggravation in both the trealment group and controls,but IgA,IgG,serum complement of C4,PaO2 level and ability of oxygenation in the arterial blood were significantly decreased(P0.01).Though the two groups showed no difference before treatment,the symptoms were relieved a lot in the patients 10 to 14 days after medication of ambroxil(P0.05).No changes occurred in the two groups with regard to IgM(P0.05).Conclusion:Ambroxol could inhibit the production and release of systemic cytokines,regulate the immune function and bost the pulmonary oxyenation in such patients,which is helpful to the recovery of patients with COPD during the acute exacerbation episode." @default.
- W2365281014 created "2016-06-24" @default.
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- W2365281014 date "2011-01-01" @default.
- W2365281014 modified "2023-09-22" @default.
- W2365281014 title "Effect of ambroxol on the immunological and respiratory function on patients with COPD during acute exacerbation" @default.
- W2365281014 hasPublicationYear "2011" @default.
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