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- W2365335228 abstract "Zinc Finger Protein is a sequence-specific transeriptional repressor, which involved in special intracellu-lar nucleic acids binding, controlling of gene expression and play important role in cell division and differentiation, embryo development and individuals growth. A novel Zinc Finger Protein Gene which is 1 809 nucleotide long, encoding a polypeptide of 143 amino acids and 1 332 bp nucleotide sequence at 3'-franking no-coding region were cloned from a cD-NA library derived from fifth instar silkgland, and was nominated as BmZFP (GenBank accession number: AY753659) . This gene was a CCHC protein with 6 putative functional domains. Although the similarity of amino acids sequence 'of this gene with those of human,mouse and rat was approximately 30% , the six functional domains of Cys (G) and His (H) were completely matched. The results of genomic organization analysis showed that BmZFP is encoded by two exons and one intron in 1 809 bp length,and the putative promoter lay between - 182 and - 222 of 5' upstream sequence relative to translation start site,however,without a typical TATA box. Cloning and structure analysis provide a basis for functional and relative gene control of BmZFP." @default.
- W2365335228 created "2016-06-24" @default.
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- W2365335228 date "2004-01-01" @default.
- W2365335228 modified "2023-09-25" @default.
- W2365335228 title "Cloning and Genomic Organization of a Novel Zinc Finger Protein Gene From Silkworm, Bombyx mori" @default.
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