FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2365361806> ?p ?o ?g. }

• W2365361806 abstract "ronchial clearance in the human lung is mainly controlled by two mechanisms: Particles deposited on the mucus layer are cleared via the mucociliary escalator, whereas particles captured in the periciliary sol phase are subject to a slow bronchial clearance, including time-independent accumulation between the cilia, uptake by airway macrophages, and endocytosis by epithelial cells. In the present contribution, these essential factors of slow bronchial clearance have been summarized in a mechanistic model and formulated mathematically. As underlined by histological studies of bronchial cells, the significance of single slow clearance parameters chiefly depends on the size of inhaled aerosols and the geometry of epithelial cilia. Therefore, small particles are mainly subject to periciliary accumulation and macrophage/epithelial uptake, whereas large particles are either stored between the cilia or re-transferred on the mucus layer after a certain time delay. According to previous publications, the slow clearance fraction has been assumed to increase exponentially from proximal to distal airway generations and to correspond with an increase of mucus discontinuities which are considered as the results of either an arrhythmic secretion of the gland cells or the thinning out and tearing of the mucus layer due to high-frequent cilia beating. A first application of the generated model allows the quantification of respective slow clearance mechanisms for each airway generation of the tracheobronchial compartment and produces preliminary results showing good agreement with present theories and available experimental data." @default.
• W2365361806 created "2016-06-24" @default.
• W2365361806 creator A5091893852 @default.
• W2365361806 date "2016-01-01" @default.
• W2365361806 modified "2023-09-27" @default.
• W2365361806 title "An Advanced Mathematical Model of Slow Bronchial Clearance in the Human Respiratory Tract" @default.
• W2365361806 cites W1499043490 @default.
• W2365361806 cites W1515469545 @default.
• W2365361806 cites W1547596640 @default.
• W2365361806 cites W1565439411 @default.
• W2365361806 cites W1722340829 @default.
• W2365361806 cites W173860571 @default.
• W2365361806 cites W1885030 @default.
• W2365361806 cites W1983562705 @default.
• W2365361806 cites W1986524556 @default.
• W2365361806 cites W1992664447 @default.
• W2365361806 cites W2001990407 @default.
• W2365361806 cites W2004414024 @default.
• W2365361806 cites W2008422771 @default.
• W2365361806 cites W2022759075 @default.
• W2365361806 cites W2023782667 @default.
• W2365361806 cites W2026141791 @default.
• W2365361806 cites W2026334270 @default.
• W2365361806 cites W2026535974 @default.
• W2365361806 cites W2026801613 @default.
• W2365361806 cites W2028203497 @default.
• W2365361806 cites W203379466 @default.
• W2365361806 cites W2042750258 @default.
• W2365361806 cites W2042857906 @default.
• W2365361806 cites W2051995167 @default.
• W2365361806 cites W2068289803 @default.
• W2365361806 cites W2072713234 @default.
• W2365361806 cites W2080406729 @default.
• W2365361806 cites W2082599617 @default.
• W2365361806 cites W2083169368 @default.
• W2365361806 cites W2083302556 @default.
• W2365361806 cites W2087222741 @default.
• W2365361806 cites W2096657544 @default.
• W2365361806 cites W2105133523 @default.
• W2365361806 cites W2122806458 @default.
• W2365361806 cites W2149128436 @default.
• W2365361806 cites W2157588663 @default.
• W2365361806 cites W2159306570 @default.
• W2365361806 cites W2278820503 @default.
• W2365361806 cites W2317771819 @default.
• W2365361806 cites W3123499353 @default.
• W2365361806 cites W601266709 @default.
• W2365361806 hasPublicationYear "2016" @default.
• W2365361806 type Work @default.
• W2365361806 sameAs 2365361806 @default.
• W2365361806 citedByCount "2" @default.
• W2365361806 countsByYear W23653618062018 @default.
• W2365361806 countsByYear W23653618062021 @default.
• W2365361806 crossrefType "journal-article" @default.
• W2365361806 hasAuthorship W2365361806A5091893852 @default.
• W2365361806 hasConcept C100094513 @default.
• W2365361806 hasConcept C105702510 @default.
• W2365361806 hasConcept C105922876 @default.
• W2365361806 hasConcept C114682108 @default.
• W2365361806 hasConcept C12554922 @default.
• W2365361806 hasConcept C126322002 @default.
• W2365361806 hasConcept C126894567 @default.
• W2365361806 hasConcept C134018914 @default.
• W2365361806 hasConcept C138944611 @default.
• W2365361806 hasConcept C141071460 @default.
• W2365361806 hasConcept C142724271 @default.
• W2365361806 hasConcept C1491633281 @default.
• W2365361806 hasConcept C18206936 @default.
• W2365361806 hasConcept C185592680 @default.
• W2365361806 hasConcept C18903297 @default.
• W2365361806 hasConcept C2777312293 @default.
• W2365361806 hasConcept C2777714996 @default.
• W2365361806 hasConcept C2779644171 @default.
• W2365361806 hasConcept C28005876 @default.
• W2365361806 hasConcept C2910722709 @default.
• W2365361806 hasConcept C49039625 @default.
• W2365361806 hasConcept C529295009 @default.
• W2365361806 hasConcept C534529494 @default.
• W2365361806 hasConcept C55493867 @default.
• W2365361806 hasConcept C71924100 @default.
• W2365361806 hasConcept C86803240 @default.
• W2365361806 hasConcept C87568996 @default.
• W2365361806 hasConcept C95444343 @default.
• W2365361806 hasConceptScore W2365361806C100094513 @default.
• W2365361806 hasConceptScore W2365361806C105702510 @default.
• W2365361806 hasConceptScore W2365361806C105922876 @default.
• W2365361806 hasConceptScore W2365361806C114682108 @default.
• W2365361806 hasConceptScore W2365361806C12554922 @default.
• W2365361806 hasConceptScore W2365361806C126322002 @default.
• W2365361806 hasConceptScore W2365361806C126894567 @default.
• W2365361806 hasConceptScore W2365361806C134018914 @default.
• W2365361806 hasConceptScore W2365361806C138944611 @default.
• W2365361806 hasConceptScore W2365361806C141071460 @default.
• W2365361806 hasConceptScore W2365361806C142724271 @default.
• W2365361806 hasConceptScore W2365361806C1491633281 @default.
• W2365361806 hasConceptScore W2365361806C18206936 @default.
• W2365361806 hasConceptScore W2365361806C185592680 @default.
• W2365361806 hasConceptScore W2365361806C18903297 @default.
• W2365361806 hasConceptScore W2365361806C2777312293 @default.
• W2365361806 hasConceptScore W2365361806C2777714996 @default.

• next