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- W2365419294 abstract "OBJECTIVE To explore the factors associated with production of extended spectrum β-lactamase-producing Escherichia coli and the measures to prevent its spread and treatment.METHODS A total of 205 E.coli strains isolated from various specimens of in patients admitted from Jan 2008 to Jan 2010 were analysed.The drug resistance of these strains were analysed using KB method recommended by CLSI.RESULTS A total of 89 ESBLs-producing E.coli were isolated from the 205 E.coli strains during the 3 years.The isolation rate was 43.5%.All ESBLs producing strains were sensitive to imipenium and amikacin and the resistancerate to nitrofurantion piperacillin/tazobactam,cefoxitin was less than 10.0%.The resistance rate remained almost the same in the 3 years.Prolon ged continuous use of antibiotics,high freguency of antibiotics usage,the use of the third generation cephalosporins,combination of antibiotics and frequent changes of antibiotics could induce the emergence of ESBLs producing strains.CONCLUSIONS The sensitivity rates of ESBLs producing strains to impenium amikacin,nitrofurantion,piperacillin/tagobactam and cefoxitin are higher than 90.0% but the strains themselves are cross-resistant and multidrug-resistant to other antibiotics.Continuous use of antibiotics for a long time,the use of third generation cephalosporin,combination of antibiotics and frequent dressing can easily lead to ESBLs-producing." @default.
- W2365419294 created "2016-06-24" @default.
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- W2365419294 date "2011-01-01" @default.
- W2365419294 modified "2023-09-24" @default.
- W2365419294 title "Drug resistance of extended spectrum β-lactamase-producing Escherichia coli and factors for enzyme production" @default.
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