FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2365425592> ?p ?o ?g. }

• W2365425592 endingPage "28" @default.
• W2365425592 startingPage "22" @default.
• W2365425592 abstract "Objectives Evaluation of pulmonary subsolid nodule is a longstanding clinical problem. We aimed to validate the computed tomography (CT) features correlating with pathological invasiveness and to explore any imaging findings associated with epidermal growth factor receptor (EGFR) mutation in lung adenocarcinoma. Methods A total of 204 patients with pathologically proven stage IA adenocarcinoma who had preoperative CT and data on EGFR status were enrolled in this retrospective study. Quantitative CT features including tumor size and solid volume proportion (SVP) were measured on multiplanar reconstructed images. Pathological analysis was stratified into adenocarcinoma in situ and minimally invasive adenocarcinoma (AIS/MIA), and invasive adenocarcinomas (IAs). Results There were 93 AIS/MIA and 111 IAs. EGFR mutation was detected in 109 (53.4%) cases. In radiopathological analysis, IAs were significantly in larger tumor size (15.8 mm vs. 10.9 mm), higher SVP (18.3% vs. 1.1%) and more likely to present air bronchogram, vascular invasion, lobulated/irregular shape, non-smooth margin and pleural tag than AIS/MIA. The multivariate logistic regression indicated that tumor size (OR = 1.337) and SVP (OR = 1.198) were significant differentiating factors of IAs from AIS/MIA. In radiogenomic analysis, EGFR status differed in tumor size, air bronchogram and margin. The multivariate logistic regression disclosed that the presence of an air bronchogram (OR = 3.451) was significantly associated with EGFR mutation after adjustment for age, gender and smoking status. Conclusions In subsolid nodules, tumor size and SVP were significant predictors of pathological invasiveness. In addition, the presence of air bronchogram was suggestive of activated EGFR mutation." @default.
• W2365425592 created "2016-06-24" @default.
• W2365425592 creator A5022621937 @default.
• W2365425592 creator A5028100325 @default.
• W2365425592 creator A5029360035 @default.
• W2365425592 creator A5042976629 @default.
• W2365425592 creator A5044161600 @default.
• W2365425592 creator A5049692788 @default.
• W2365425592 creator A5052226334 @default.
• W2365425592 creator A5054703619 @default.
• W2365425592 creator A5060808786 @default.
• W2365425592 creator A5090693810 @default.
• W2365425592 date "2016-08-01" @default.
• W2365425592 modified "2023-09-23" @default.
• W2365425592 title "Air bronchogram: A potential indicator of epidermal growth factor receptor mutation in pulmonary subsolid nodules" @default.
• W2365425592 cites W130099911 @default.
• W2365425592 cites W1487507663 @default.
• W2365425592 cites W1972555780 @default.
• W2365425592 cites W2018048200 @default.
• W2365425592 cites W2040096495 @default.
• W2365425592 cites W2041863601 @default.
• W2365425592 cites W2046810386 @default.
• W2365425592 cites W2049674541 @default.
• W2365425592 cites W2068638242 @default.
• W2365425592 cites W2086628063 @default.
• W2365425592 cites W2095868657 @default.
• W2365425592 cites W2098117936 @default.
• W2365425592 cites W2100047106 @default.
• W2365425592 cites W2102191747 @default.
• W2365425592 cites W2102634410 @default.
• W2365425592 cites W2114175038 @default.
• W2365425592 cites W2115968294 @default.
• W2365425592 cites W2129360604 @default.
• W2365425592 cites W2129597285 @default.
• W2365425592 cites W2134953630 @default.
• W2365425592 cites W2136844032 @default.
• W2365425592 cites W2140124489 @default.
• W2365425592 cites W2158734599 @default.
• W2365425592 cites W2163149604 @default.
• W2365425592 cites W2172168307 @default.
• W2365425592 cites W2268116731 @default.
• W2365425592 cites W2313039124 @default.
• W2365425592 cites W2316080280 @default.
• W2365425592 cites W4362175132 @default.
• W2365425592 cites W4376848671 @default.
• W2365425592 cites W828015039 @default.
• W2365425592 doi "https://doi.org/10.1016/j.lungcan.2016.05.009" @default.
• W2365425592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27393502" @default.
• W2365425592 hasPublicationYear "2016" @default.
• W2365425592 type Work @default.
• W2365425592 sameAs 2365425592 @default.
• W2365425592 citedByCount "34" @default.
• W2365425592 countsByYear W23654255922017 @default.
• W2365425592 countsByYear W23654255922018 @default.
• W2365425592 countsByYear W23654255922019 @default.
• W2365425592 countsByYear W23654255922020 @default.
• W2365425592 countsByYear W23654255922021 @default.
• W2365425592 countsByYear W23654255922022 @default.
• W2365425592 countsByYear W23654255922023 @default.
• W2365425592 crossrefType "journal-article" @default.
• W2365425592 hasAuthorship W2365425592A5022621937 @default.
• W2365425592 hasAuthorship W2365425592A5028100325 @default.
• W2365425592 hasAuthorship W2365425592A5029360035 @default.
• W2365425592 hasAuthorship W2365425592A5042976629 @default.
• W2365425592 hasAuthorship W2365425592A5044161600 @default.
• W2365425592 hasAuthorship W2365425592A5049692788 @default.
• W2365425592 hasAuthorship W2365425592A5052226334 @default.
• W2365425592 hasAuthorship W2365425592A5054703619 @default.
• W2365425592 hasAuthorship W2365425592A5060808786 @default.
• W2365425592 hasAuthorship W2365425592A5090693810 @default.
• W2365425592 hasConcept C121608353 @default.
• W2365425592 hasConcept C126322002 @default.
• W2365425592 hasConcept C126838900 @default.
• W2365425592 hasConcept C142724271 @default.
• W2365425592 hasConcept C143998085 @default.
• W2365425592 hasConcept C151730666 @default.
• W2365425592 hasConcept C151956035 @default.
• W2365425592 hasConcept C207886595 @default.
• W2365425592 hasConcept C2776731575 @default.
• W2365425592 hasConcept C2777714996 @default.
• W2365425592 hasConcept C2779438470 @default.
• W2365425592 hasConcept C2781182431 @default.
• W2365425592 hasConcept C38180746 @default.
• W2365425592 hasConcept C71924100 @default.
• W2365425592 hasConcept C86803240 @default.
• W2365425592 hasConceptScore W2365425592C121608353 @default.
• W2365425592 hasConceptScore W2365425592C126322002 @default.
• W2365425592 hasConceptScore W2365425592C126838900 @default.
• W2365425592 hasConceptScore W2365425592C142724271 @default.
• W2365425592 hasConceptScore W2365425592C143998085 @default.
• W2365425592 hasConceptScore W2365425592C151730666 @default.
• W2365425592 hasConceptScore W2365425592C151956035 @default.
• W2365425592 hasConceptScore W2365425592C207886595 @default.
• W2365425592 hasConceptScore W2365425592C2776731575 @default.
• W2365425592 hasConceptScore W2365425592C2777714996 @default.
• W2365425592 hasConceptScore W2365425592C2779438470 @default.
• W2365425592 hasConceptScore W2365425592C2781182431 @default.
• W2365425592 hasConceptScore W2365425592C38180746 @default.

• next