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- W2365430170 abstract "Objective To culture rat mesenchymal stem cells(MSCs)and explore the protective effects of MSCs on the renal grafts.Methods Bone marrow was collected from SD rats by flushing femurs and tibias under sterile condition.MSCs were purified by density gradient centrifugation or stillness-stick- cultivation in vitro.Sixty Wistar rats were transplanted with the left kidneys of SD rats and divided into fol- lowing groups(n=20 in each group):MSCs group(groupⅠ),control group(groupⅡ)and cyclospo- fine group(groupⅢ).The survival time and morphology of the renal grafts were observed.Results MSCs that were in low abundance grew quickly when cultured in vitro.The survival time of groupⅠ[(15.50 d±6.35)days]and groupⅢ[(18.50±5.97)days]were longer than in groupⅡ[(6.50±3.11)days].In the groupsⅠandⅢ,the changes of the renal grafts were milder than in groupⅢ.Con- clusion MSCs can be isolated,cultured and expanded easily in vitro,and have protective effect on the re- nal graft in early period." @default.
- W2365430170 created "2016-06-24" @default.
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- W2365430170 date "2007-01-01" @default.
- W2365430170 modified "2023-09-23" @default.
- W2365430170 title "Protective effect of bone marrow-derived mesenchymal stem cells infusion on the renal grafts" @default.
- W2365430170 hasPublicationYear "2007" @default.
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