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- W2365431714 abstract "Objective To discuss the effective solvent extracts on mice model of kidney-yang deficiency.Methods After mice model of kidney-yang deficiency prepared with the high dose Hydrocortisone,the groups were treated with high,middle and low dose of different solvent extracts respectively,according to the design.Weight growth rates,organ coefficients were observed,and evaluated the histopathological changes of kidney and hypothalamus.Rusults(1)The systemic depletion induced by high dose cortical hormone was shown in kidney-yang deficiency group,but the three solvent extracts of Diaphragma Juglandis Fructus,n-butanol extract group,distilled water solvent extract group could improve the depletion at different degree;(2) In term of mice′s body weight and organ coefficients,each of the group show ED improving effects at different degree compared to the control group and Kidney-yang Deficiency group;(3) The high dose n-butanol extract group and low dose 95% ethanol group could decrease glomerular capillary permeability,and could resist the capillary telangiectasis;low dose 95% ethanol group and middle dose distilled water group could significantly improve the edema of renal tubular epithelial cells;n-butanol group(high,middle and low) and distilled water solvent extract group(high,middle) could improve the edema of glial cells.Conclution The 95% ethanol solvent extract,n-butanol solvent extract and distilled water solvent extract of Diaphragma Juglandis Fructus can improve the mice′s symptoms of kidney-yang deficiency at different degrees." @default.
- W2365431714 created "2016-06-24" @default.
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- W2365431714 date "2012-01-01" @default.
- W2365431714 modified "2023-09-25" @default.
- W2365431714 title "Study of Uygur medicine diaphragma juglandis fructus on mice model of kidney-yang deficiency" @default.
- W2365431714 hasPublicationYear "2012" @default.
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