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- W2365484539 abstract "Objective To evaluate the efficacy of intralesional Diprospan(compound betamethasone) injection therapy and high dose steroid pulse therapy with methylprednisolone in patients with multifocal alopecia areata lasting more than 13 months. Methods Twenty-third patients with localized multifocal alopecia areata of scalp lasting from 13 months to 6 years were treated with Diprospan topical intralesional injection therapy( given at 0.1?ml/cm 2). We tried intravenous high-dose corticosteroid therapy with methylprednisolone in seven cases unyielding to Diprospan intralesional therapy, given at 500?mg per day,three times monthly for 3 months. Results After two months of topical diprospan 11 cases had 50% or more improvement and less than 50% hair regrowth in 3 cases and no or poor regrowth of hair in 9 cases. With methylprednisolone pulse dosing therapy, 4 of the 7 cases had improved with regrowth of hair over 50% after three months. Conclusion Our results indicated that topical intralesional therapy with diprospan and intravenous methylprednisolone pulse dosing therapy are effective and well tolerated in longstanding and multifocal alopecia areata. We consider intravenous high-dose corticosteroids as an alternative therapy in severe alopecia areata anyielding to other treatment." @default.
- W2365484539 created "2016-06-24" @default.
- W2365484539 creator A5068775680 @default.
- W2365484539 date "2003-01-01" @default.
- W2365484539 modified "2023-09-24" @default.
- W2365484539 title "Steroid topical therapy and pulse dosing therapy for multifocal alopecia areata" @default.
- W2365484539 hasPublicationYear "2003" @default.
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