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- W2365484603 abstract "Objective To observe the changes of skin microcirculation perfusion discharge(MPD)and the effect of pentoxifylline on rabbits after high-voltage electrical burn(HEB).Methods Forty five rabbits were divided into control group,electrical burn group and pentoxifylline treatment group in a simple random method,with 15 rabbits in each group.Rabbit model of HEB was reproduced from electrical burn with the TC-30-20KVA type voltage regulator and YDJ-10KVA type transformer.The control group was not electric shock.The LISCA Laser Doppler Hemoperfusion image instrument(LDPI)was used to observe the changes of skin MPD at 5 minutes before the HEB,5 minutes,1 hour,2 hours,4 hours and 8 hours later.The locations observed were wound surface skin of left forelimb and right hindlimb,normal skin of right forelimb and left hindlimb.Results(1)The MPD of wound surface and normal skin in four limbs of electrical burn group and pentoxifylline treatment group after HEB were discreased,compared with that before HEB.At 5 minutes after HEB,the skin MPD of left forelimb of electrical burn group and pentoxifylline treatment group were(0.66±0.13)V,(1.62±0.27)V,but they were(0.59±0.12)V,(1.50±0.23)V in left hindlimb.These values were less than before HEB [(3.21±0.22),(3.24±0.25),(3.06±0.24),(3.01±0.22)V].(2)Compared with the same group right limbs in electrical burn group and pentoxifylline treatment group,the MPD of wound surface in left limbs was less than normal skin.(3)The MPD of wound surface and normal skin in electrical burn group was less than control group.Pentoxifylline treatment group and electrical burn group had the same tendency.(4)The MPD of normal skin in pentoxifylline treatment group was more than electrical burn group after HEB.Compared with the MPD of wound surface,there were not significant differentces.Conclusions The MPD of wound surface and normal skin decreases after HEB.Pentoxifylline can improve MPD of normal skin,but show no effect on wound surface skin." @default.
- W2365484603 created "2016-06-24" @default.
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- W2365484603 date "2010-01-01" @default.
- W2365484603 modified "2023-09-27" @default.
- W2365484603 title "Dynamic alteration of skin microcirculation and effect of pentoxifylline on rabbits after experimental high-voltage electrical burn" @default.
- W2365484603 hasPublicationYear "2010" @default.
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