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- W2365489320 abstract "Objective To study the protective effects of Chuanhuang-sanqi medicinal broth on the external jugular vein after being transplanted into femoral artery and explore its possible mechanism. Methods Autogenous vein grafts model was established in 50 rabbits. Interposition jugular vein were transplaced into carotid artery of the rabbits by microsurgical technique. Animals received Chuanhuang-sanqi medicinal broth. The control group given normal saline by oral gavage 72 hours before and then daily after surgery. Interposition jugular vein were transplanted into femoral arteries of the rabbits by microsurgical technique. grafting veins weresampled after 4 weeks,At the same time take normal vein did not refer to the opposite side of vein graft. The veins were cut into 2 segments. One was for endothelial integrity grading by SEM examination. The other was interposed between contralateral common carotid arteries. The vein grafts were harvested at 2 weeks after grafting. Neintimal square-to-luminal square ratio(S1/S2)was measured with a computerized image analysis system. Result The stenosis of grafted veins: 4 weeks later, the jugular veins′ intima/media membrane of all the operative groups were signifi cantly thicker than The normal control group. There were signifi cant differences between every two group(P0.05). Conclusion Chuanhuang-sanqi medicinal broth can lessen the thickness of arterialized vein′s intima/media membrane and lighten the stenosis of the bridging vein." @default.
- W2365489320 created "2016-06-24" @default.
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- W2365489320 date "2010-01-01" @default.
- W2365489320 modified "2023-09-23" @default.
- W2365489320 title "Study on the Prevention of Autologous Vein Graft Restenosis by Chuanhuang-sanqi Medicinal Broth" @default.
- W2365489320 hasPublicationYear "2010" @default.
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