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- W2365539015 abstract "Objective To study the pharmacological action of anti-inflammation, acesodyne, and anti-diarrhea of Fufangshanqikeliji (FFSQKLJ). Methods FFSQKLJ were poured consecutively into the stomach of healthy Wistar rats and Kunming mice, respectively. Then three kinds of models were set up 1 h after administration: inflammation models of the tumefaction of back metatarsus in rats by hypodermic injection (1% carrageenin 0.1 mL), ache models of twist in mice by celiac injection (0.7% glacial acetic acid 10 mL·kg~ -1), diarrhea models in mice after pouring the senna. At the same time, control group (0.5% sodium carboxymethyl cellulose 20 mL·kg~ -1) and salicylazosulfapyridine (SASP, 0.5 g·kg~ -1·d~ -1) group were set up. The tumefaction extents of back metatarsus of rats before and after inflammation, times of every mouse twist in 30 minutes after celiac injection (0.7% glacial acetic acid 10 mL·kg~ -1), times of abnormal excretion in 1-6 h after pouring the senna, respectively, were observed. Results The tumefaction rates of back metatarsus in rats in the middle and large dosages of FFSQKLJ groups were much lower than that in control group (P0.05 ), and the times of twist in mice were much lower than that in control group (P0.05). Large, middle and small dosages of FFSQKLJ reduced the times of diarrhea in mice, compared with the control group, the differences were very obvious (P0.05) . Conclusion FFSQKLJ have good effects of anti-inflammation, acesodyne, and anti-diarrhea." @default.
- W2365539015 created "2016-06-24" @default.
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- W2365539015 date "2005-01-01" @default.
- W2365539015 modified "2023-09-25" @default.
- W2365539015 title "Pharmacological research on Fufangshanqikeliji" @default.
- W2365539015 hasPublicationYear "2005" @default.
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