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- W2365554203 abstract "OBJECTIVE To establish an RP-HPLC method for the determination of Lederfea in human plasma.METHODS Seperation was performed on a Kromail C18 column and the detection wewelength was set at 285 nm.The mobile phase was the mixture of methanol and 0.02 mol L-1of KH2PO4 and acetonitrile(70:25:5) at a flow rate of 1.0 ml·min-1.RESULTS The linear range was 0.16-16.0 mg·L-1,r=0.9993.The lowest limit of quantification was 0.16 mg·L-1.The extraction recovery was 98.32%-103.47%.The RSD of intra-day were 2.91%-3.86% and 2.96-4.97%,resp ectively.CONCLUSION The method is simple,quick,accurate,and is suitable for the determination of lederfea concentration in human plasma and pharmacokinetic studies." @default.
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- W2365554203 date "2009-01-01" @default.
- W2365554203 modified "2023-09-23" @default.
- W2365554203 title "Determination of lederfea concentration in human plasma by RP-HPLC" @default.
- W2365554203 hasPublicationYear "2009" @default.
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