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- W2365599251 abstract "The experiment was conducted to research the effect of thiram on growth performance and histopathologic changes of tibial dyschondroplasia in broilers.160 one-day-old AA broilers were randomly allotted into two treatments after raised seven days,they were given a regular diet(control group),or the same diet containing thiram 100 mg/kg for 96 h,then control and experimental group broilers were given the same regular diet.The feeding experiment was ended at 23rd days.ADG,F/G,TD score and TD incidence were studied at 4th,9th,16th,23rd day.Pathological and histopathologic changes of growth plate were also observed at different stages.The results showed that TD incidence was 94.44% at 4th day.Body weight was decreased at 4th and 9th day,and feed to gain ratio(F/G) was increased at 4th day.The pathological symptoms were typical but also more severe than those of spontaneous TD.Through every stage observing with microscope,we found that the thiram promoted chondrocyte proliferation,resulted in large numbers of death cells,compressed blood vessels which led to necrosis of blood vessel,hindered extracellular matrix synthesis,deferred endochondral calcification,formed cartilage plug finally because of accumulated prehypertrophic chondrocytes.As a result,it was demonstrated that thiram could decline growth performance and elevate TD incidence significantly,lead to pathological and histopathologic changes in growth plate,which were similar to those of spontaneously occurring TD.So broiler TD induced by thiram is an ideal animal model for studying TD development and selecting effective different micronutrients against TD." @default.
- W2365599251 created "2016-06-24" @default.
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- W2365599251 date "2008-01-01" @default.
- W2365599251 modified "2023-09-28" @default.
- W2365599251 title "Effect of Thiram on Growth Performance and Histopathologic Changes of Tibial Dyschondroplasia in Broiler" @default.
- W2365599251 hasPublicationYear "2008" @default.
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