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- W2365607077 abstract "Objective:To observe the pulmonary lesions of rats with bronchopulmonary dysplasia.Methods:30 4-days-old female rats were divided into control group(FiO20.21,n=15) and model group(FiO20.6,n=15) randomly.Pathomorphological changes,ultramicrostucture and collagen level were detected on the seventh days,fourteenth days and twenty-first days after experiment.Results:Stained by HE,lungs of model group showed destroy of alveoli,alveoli fusion and increased septal wall thickness,radical alveolar counts were significantly lower than those in model group(P0.001).Stained by sirius rosebb,the expression levels of collagen Ⅰ and collagen Ⅲ increased,collagen area was significantly higher than that of control group(P0.001).Lamellar bodies and microvilli of model group decreased under electron microscope.Conclusion:Long-term exposure to oxygen of high concentration can induce bronchopulmonary dysplasia-like lesions in lung structure of rats." @default.
- W2365607077 created "2016-06-24" @default.
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- W2365607077 date "2009-01-01" @default.
- W2365607077 modified "2023-09-23" @default.
- W2365607077 title "Pulmonary lesions of rats with bronchopulmonary dysplasia" @default.
- W2365607077 hasPublicationYear "2009" @default.
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