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- W2365622020 abstract "The transportation of piglets results in stress that is associated with increased susceptibility to diseases,presumably due to alteration of immune function and antioxidative ability.The objective of present study was to determine if a 2 h transportation of piglets by road induced changes in antioxidative ability and proinflammatory cytokines.Thirty piglets weighting about 20 kg were divided into experimental and control group on the average.The animals in experimental group were transported by truck on road for 2 h.Then hearts and livers were collected,blood was harvested from all piglets.The antioxidative capacity of hearts and livers and serum concentration of IL-1β and IL-2 were assayed.The result were as follows,the antioxidative ability was not obviously changed in hearts after transportation,although production of reactive oxygen species(ROS) in hearts of transported animals was greater than that of control group(P0.05).In livers,the activities of total antioxidative capacity(T-AOC) and catalase(CAT) were obviously decreased(P0.05) following transportation,and the decrease was accompanied with significant rise of the maleic dialdehyde(MDA) concentration(P0.05).Cu-Zn superoxide dismutase(Cu-Zn SOD),a important antioxidative enzyme,was down-regulated in hearts and livers following transportation in mRNA level(P0.05).The serum contents of proinflammatory cytokines IL-1β and IL-2 were risen slightly.It was concluded that 2 h transportation of piglets induces decrease of antioxidative capacity only in the liver and increase of proinflammatory cytokines of IL-1β and IL-2 concentration in sera slightly.It was indicated that the decreased antioxidative capacity and increased proinflammatory cytokine concentration lead to tissue lesion of piglets following transportation." @default.
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- W2365622020 date "2009-01-01" @default.
- W2365622020 modified "2023-09-23" @default.
- W2365622020 title "Effect of Transportation on the Antioxidative Capacity and Proinflammatory Cytokines in Piglets" @default.
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