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- W2365626646 abstract "Objective To evaluate the diversity of clinical manifestation and factors causing misdiagnosis of Crohn's disease. Methods Thirty patients of active Crohn's disease were studied. All their diagnostic and therapeutic data were analysed. Results Most patients were young adults, with a 1.14∶1 female predominance in prevalence. The disease affects any segment or a combination of segments of the alimentary tract from mouth to anus. In particular, the colon and small bowel were the major sites involved. Recurrent episodes of abdominal pain and watery diarrhea were the most common symptoms. Low grade fever, emaciation, anemia, and skin, joint and perianal symptoms could be found. Endoscopy combined with histologic examination of biopsy specimens provided characteristic features with a diagnostic accuracy of 52.9%. Granulomas were identifiable in 30.8% of all biopsy specimens. Transabdominal bowel sonography (TABS) can be used to detect intestinal complications. Factors causing misdiagnosis were: ① insufficient understanding of the disease; ② diverse clinical presentations; ③ over emphasis on the diagnostic value of granulomas in Crohn's disease.Conclusions Crohn's disease is not uncommon in China. Abdominal pain and watery diarrhea are two major symptoms. Endoscopy (with biopsy), and transabdominal bowel sonography were both valuable procedures for diagnosis." @default.
- W2365626646 created "2016-06-24" @default.
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- W2365626646 date "2002-01-01" @default.
- W2365626646 modified "2023-09-24" @default.
- W2365626646 title "Crohn's disease and its diverse clinical presentations" @default.
- W2365626646 hasPublicationYear "2002" @default.
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