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- W2365638271 abstract "Objective:To observe the effect of Xingnaojing injection(XNJ)on malondial dehyde(MDA),six-eight superoxide dismutase(SOD),tumor necrosis factor-α(TNF-α),interleukin-8(IL-8) in patients with acute brain injury,and investigate brain protective mechanism of XNJ.Method: 68 patients with severe craniocerebral injury were divided randomLy into experimental group and control group,34 cases in each group.Conventional therapy was used in control group.On the base of control group,30 mL XNJ with 5% glucose injection 500 mL were used in experimental group(once a day,10 days a course).MDA,SOD,TNF-α,IL-8 were measured before therapy and after therapy.Result: Compared with that before therapy,Glasgow comascale(GCS) and SOD increased,MDA and TNF-α and IL-8 decreased significantly in experimental groups(P0.05 or P0.01).Compared with that in control group,GCS and SOD increased,MDA,TNF-α and IL-8 decreased in experimental groups,there was a significant difference(P0.05 or P0.01).Conclusion: XNJ can activate SOD,remove intracalvarium oxygen radicals,inhibit inflammatory factor such as TNF-α,and then improve consciousness of brain injury patients." @default.
- W2365638271 created "2016-06-24" @default.
- W2365638271 creator A5081537162 @default.
- W2365638271 date "2011-01-01" @default.
- W2365638271 modified "2023-09-23" @default.
- W2365638271 title "Effect of Xingnaojing Injection on MDA,SOD,TNF-α,IL-8 in Patients with Acute Brain Injury" @default.
- W2365638271 hasPublicationYear "2011" @default.
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