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- W2365642907 abstract "Objective To observe the effect of inducible nitric oxide synthase inhibitor L NIL (L N 6 iminoethyl lysine) on cellular energy metabolism and survival rate in cecum ligation puncture (CLP) model. Methods 0 9% natrii sodium or L NIL or L NIL + L Arg was injected into CLP mice respectively. The mitochondrial structure of liver cell, the content of ATP and the ratio of ATP/ADP of cardiomyocyte and the survival rate of mice were compared between groups. Results The damage of mitochondrial structure was attenuated, the content of ATP and the ratio of ATP/ADP of cardiomyocyte was increased,and the 18th hour survival rate raised from 20% to 60% in CLP mice with L NIL administration. Conclusion L NIL can improve the myocardium energy metabolism and raise the survival rate in CLP mice." @default.
- W2365642907 created "2016-06-24" @default.
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- W2365642907 date "1999-01-01" @default.
- W2365642907 modified "2023-09-28" @default.
- W2365642907 title "Effect of L NIL on cellular energy metabolism and survival rate in sepsis mice" @default.
- W2365642907 hasPublicationYear "1999" @default.
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