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- W2365645549 abstract "Objective To study the effect of alprostadil combined with Shenmai or astragalus on diabetic nephropathy(DN).Methods Ninety cases of DN patients were randomly divided into control group,treatment group A and treatment group B.The patients of control group were treated with alprostadil,treatment group A alprostadil combined with Shenmai,and treatment group B alprostadil with astragalus.Two weeks was a course,altogether two courses.The clinical indexes were evaluated before and after the treatment.Serum interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and Toll-like receptor 4(TLR4)were also detected by ELISA.Results Clinical indexes of patients were improved in all three groups after treatment.Total effective rate of group A and group B were 90.0%and 93.3%,which were remarkably higher compared with that of control group(63.3%)(all P 0.05).The levels of serum IL-6,TNF-αand TLR4were significantly decreased in group A and B.Conclusion Treating DN with alprostadil combined with Shenmai or astragalus has refined clinical effect without serious untoward effect." @default.
- W2365645549 created "2016-06-24" @default.
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- W2365645549 date "2014-01-01" @default.
- W2365645549 modified "2023-09-28" @default.
- W2365645549 title "Effect of alprostadil combined with Shenmai or astragalus in treatment of diabetic nephropathy" @default.
- W2365645549 hasPublicationYear "2014" @default.
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