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- W2365651457 abstract "Forty-five adult female SD rats were separated into control group,lead acetate group(300mg/L),lead acetate+N-acetyl cysteine(NAC)(300mg/L+20mmol/L) group,cadmium chloride group(10mg/L),cadmium chloride+NAC group(10mg/L+20mmol/L),group of low doses of lead and cadmium(150mg/L+5mg/L),group of low doses of lead and cadmium+NAC(150mg/L+5mg/L+20mmol/L),and group of high doses lead and cadmium(300mg/L+10mg/L),group of high doses of lead and cadmium+NAC(300mg/L+10mg/L+20mmol/L),and the additives were given in the drinking water.After gestational periods the activities of SOD,MDA,GSH-Px,TChE and CAT in brain were analyzed respectively.The results showed that low doses of lead and cadmium appeared the intermediate effects(between toxicity of single Pb and Cd),whereas high doses showed the additive effects.Compared the NAC antagonistic groups with the poisoning groups,activities of SOD,GSH-Px,TChE,and CAT increased to certain extent,but content of MDA significantly decreased.The results indicated that NAC could increase antioxidant effects and reduce lipid peroxidation in SD rats." @default.
- W2365651457 created "2016-06-24" @default.
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- W2365651457 date "2008-01-01" @default.
- W2365651457 modified "2023-09-26" @default.
- W2365651457 title "Lipid peroxidation of combined exposure to lead and cadmium and antagonism of N-acetyl cysteine in neonatal brain to pregnant rats" @default.
- W2365651457 hasPublicationYear "2008" @default.
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