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- W2365659902 abstract "[Objective] To investigate the differentiation potential of mouse me senchymal stem cells into hematopoietic cells in vivo. [Methods] Donor MSCs we re derived from transgenic mice bone marrow, and BALB/C mice pretreated with sub lethal irradiation provided a recipient for transplantation. The differentiatio n potential of MSCs in BALB/C mice was studied. 60 days after transplantation, t he marrow hematopoietic stem cells were cultured in semisolid methylcellulose me dium and then were identified by X-Gal dye, the live was also identified by X-Ga l dye. [Results] After 60 days, in both control and experimental groups, hemat opoietic colony of cobblestone shape would appear by semisolid methylcellulose c ulture of bone marrow cells, but only the experimental group became blue after X -Gal dye, the result of the liver was same. [Conclusion] The transgene mouse′ s MSCs have the ability to differentiate into hematopoietics stem cells/ progen itor cells." @default.
- W2365659902 created "2016-06-24" @default.
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- W2365659902 date "2005-01-01" @default.
- W2365659902 modified "2023-09-23" @default.
- W2365659902 title "Preliminary study on hematopoietic differentiation potential after culture-expanded transgenic mice′s MSCs transplantation in BALB/C mice" @default.
- W2365659902 hasPublicationYear "2005" @default.
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