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- W2365713090 abstract "Objective To explore the effect of soluble intercellular adhesion molecule-1 (sICAM-1) in pathogenesis of rheumatoid arthritis(RA).Methods 34 RA patients and 30 healthy subjects were included in the study. We detected the sICAM-1 levels of serum and synovial fluid in RA patients by the radioimmunoassay.Results The level of serum sICAM-1 of RA patients was significantly higher than that in control subjects(P0.001).Untreated cases was higher than clinical recovered ones(P0.001),and there was of no significant difference between the untreated patients and the recurrent patients(P0.05).The sICAM-1 level in synovial fluid of RA patients was greatly increased than the ones with the level of serum sICAM1 (P0.05),there was of no significant difference between the untreated cases and the recurrent ones(P0.05).Conclusion sICAM-1 plays a vital role in the pathogenesis of RA. The level of sICAM-1 may become an important index to judge illness condition,which can also be used for the monitoring of the activity and therapeutic effect of RA." @default.
- W2365713090 created "2016-06-24" @default.
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- W2365713090 date "2009-01-01" @default.
- W2365713090 modified "2023-09-24" @default.
- W2365713090 title "Study of rheumatoid arthritis and soluble intercellular adhesion molecule-1" @default.
- W2365713090 hasPublicationYear "2009" @default.
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