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- W2365720802 abstract "Objective To evaluate the efficacy of CsA substituting for tacrolimus (FK506) in the treatment of chronic rejection. Methods Ten patients with chronic rejection received the treatment of FK506 substituting for CsA. The initial dose of FK506 was 0.1 ～ 0.15 ?mg·kg -1 ·d -1 . Subsequently the concentration of FK506 was adjusted to maintain its whole blood trough levels between 5～10?ng/ml. Results Six of the 10 patients had decreases of blood creatinine as compared with that (400?μmol/L) before treatment of FK506. The symptoms of hypertension and renal function disorder were significantly improved. Conclusion The therapeutic effects of FK506 substituting for CsA in the treatment of early chronic rejection following renal transplantation were satisfactory." @default.
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- W2365720802 date "2001-01-01" @default.
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- W2365720802 title "Therapeutic effects of tacrolimus in the treatment of the early chronic rejection of renal transplantation" @default.
- W2365720802 hasPublicationYear "2001" @default.
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