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- W2365751452 abstract "ObjectiveTo research the expression of cell-cycle associated factor cdt1 in children with acute lymphoblastic leukemia.MethodsSixteen children with acute lymphoblastic leukemia were firstly dianosed and were not treated(research group) and 16 healthy children(control group) whose intravenous blood was collected for isolating the single-nucleus cell were controls.The expression of cdt1 in children was measured by immunohistochemistry for protein,and by reverse transcription-polymerase chain reaction(RT-PCR) for their mRNA.The data was analyzed by using software SPSS11.5 for windows.ResultsThe expression of cdt1 proteins in research group was obviously higher than those in control group(P0.05);the expression of cdt1 mRNA in research group was obviously higher than those in control group(P0.05);the cdt1 proteins were expressed,but the expression levels of their corresponding mRNA were not measured in control group.ConclusionCdt1 is related to cell cycle.The expression of cdt1 will result in the development of acute lymphoblastic leukemia;the cdt1 proteins are not related to the expression level of the corresponding mRNA in control group." @default.
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- W2365751452 date "2007-01-01" @default.
- W2365751452 modified "2023-09-28" @default.
- W2365751452 title "Expression of cell-cycle associated factor cdt1 in children with acute lymphoblastic leukemia" @default.
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