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- W2365783203 abstract "Objective To study the effect of hyperbaric oxygen preconditioning(HBO-PC) on axon regeneration after spinal cord injury in rats and investigate the neuroprotection of HBO-PC.Methods Forty female Sprague-Dawley adult rats,weighing from 250 to 300 g,were randomly divided into 2 groups,HBO-PC group(n=20) and normal injury group(n=20).The rat spinal cord injury models were established by Allen's method.Anterograde and retrograde tracing of nerve-tract were performed using biotin dextran amine(BDA) and horseradish peroxidase(HRP) respectively 8 w after the injury model was established.The regenerated neuraxis was observed ascendingly and descendingly(2 cm away from the spinal cord injury) by immunohistochemical staining to identify the effect of HBO-PC on neuraxis regeneration.Results Nerve-tract tracing revealed that the number of BDA-positive and HRP-positive fibers around the injury in HBO-PC group was significantly greater than that in normal injury group.Conclusion HBO-PC can protect the neuron from injury by inducing the axon regeneration after spinal cord injury." @default.
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- W2365783203 date "2011-01-01" @default.
- W2365783203 modified "2023-10-02" @default.
- W2365783203 title "Effect of hyperbaric oxygen preconditioning on axon regeneration after spinal cord injury in rats" @default.
- W2365783203 hasPublicationYear "2011" @default.
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