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- W2365808138 abstract "Objective To study the cerebral protection of magnesium sulfate and its effect on Glu in the acute stage of cerebral infarction Methods All the 48 patients with acute cerebral infarction were randomly and blindly divided into two groups in this study :treated group and control group The MgSO 4 was given to the patients of treated group by intravenous drip in the acute stage of cerebral infarction The level of plasma Glu was detected by high-performance liquid chromatography before the treatment and at 3 and 14 days after treatment The scores of neurological deficits in convalescence in ACI patients were also evaluated Results The plasma Glu level in patiens with acute cerebral infarction was very significantly elevated ( P 0 01)in the early stage of ACI The level of plasma Glu in the patients of treated group with MgSO 4 decreased more rapidly than that of control group without MgSO 4 at 3 days after treatment and a significant difference ( P 0 05) was found between two groups The level of plasma Glu in the patients of both groups returned to the normal level at 14 days after treatment and there was no significant difference ( P 0 05) between two groups A better curative effect was also observed in ACI patients who were treated with MgSO 4 Conclusion MgSO 4 has a neuroprotective effect on neuronal damage in the acute stage of cerebral infarction and this may be related to the action that MgSO 4 can decrease the level of Glu in plasma and weaken the excitotoxicity of Glu [" @default.
- W2365808138 created "2016-06-24" @default.
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- W2365808138 date "2004-01-01" @default.
- W2365808138 modified "2023-09-23" @default.
- W2365808138 title "Cerebral protection of magnesium sulfate and its effect on GLU in the acute stage of cerebral infarction" @default.
- W2365808138 hasPublicationYear "2004" @default.
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