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- W2365877711 abstract "Objective: To study the effects of pharmaco-serum from rabbits administrated intragastrically with Fuzheng Jiedu decoction(FJD) on injured human bronchial epithelial(16HBE) cells exposed to nickel sulfate(NiSO4).Methods: Cultured 16HBE cells were treated with both NiSO4 and different doses of FJD pharmaco-serum in vitro.The detections of cell activities and viabilities were carried out.Meanwhile,activities of glutathione peroxidase(GSH-Px) and superoxide dismutase(SOD) as well as maleic dialdehyde(MDA) contents were measured.Results: FJD pharmaco-serum could decrease mortalities and increase viabilities of 16HBE cells exposed to NiSO4.In cells co-treated with NiSO4 and FJD pharmaco-serum,the content of MDA was decreased,while GSH-Px and SOD activities were increased at the same time.High dose of FJD pharmaco-serum had the most dramatic effect.Conclusion: This study suggested that FJD could antagonize NiSO4-induced toxicity,which may be involved in its antioxidant function." @default.
- W2365877711 created "2016-06-24" @default.
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- W2365877711 date "2008-01-01" @default.
- W2365877711 modified "2023-09-28" @default.
- W2365877711 title "Effects of FuzhengJiedu decoction on antioxidant enzyme activity and MDA contents of human bronchial epithelial cells exposed to NiSO_4" @default.
- W2365877711 hasPublicationYear "2008" @default.
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